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Treatment Efficacy in Autism Spectrum Disorders

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1.  A randomized controlled trial is:
  1. required for the establishment of efficacy of any treatment
  2. considered a gold standard in efficacy studies
  3. conducted using single participant design
  4. not available for any current treatments for ASD
2.  One advantage of single participant design in investigating a treatment is:
  1. it compares group means across treatments
  2. it can show whether a treatment is generalizable to new groups
  3. it controls for individual variability by using a participant as his own control
  4. it is the most widely used approach for testing new medications
3.  ASD poses particular challenges for efficacy research because:
  1. most children are undergoing several treatments at once
  2. individual differences in this disorder are very large
  3. comorbid disorders occur at a very high rate in this population
  4. all of the above
4.  Which of the following are warning signs that can distinguish a scientific study from psuedoscience?
  1. not able to retest
  2. grandiose outcomes
  3. lack of peer review
  4. all of the above
5.  Which of the following could pose a threat to the internal validity of a research study?
  1. normal development and change
  2. the placebo effect
  3. any change introduced at the same time as the intervention
  4. all of the above
6.  Which of the statements below is the best characterization of current evidence for early intensive behavioral intervention (EIBI) for ASD?
  1. EIBI is the only valid and reliable method for the treatment of ASD
  2. EIBI is effective with all age groups
  3. EIBI has a large body of evidence to support it, but results are not uniformly positive
  4. EIBI has no good evidence to support it
7.  Which of the following best characterizes the evidence for ASD treatments for older children and adults?
  1. The evidence from the studies on young children can be applied to any age group.
  2. There is more evidence supporting ASD intervention with older children and adults than young children
  3. There are many large clinical trials on intervention approaches with older children and adults with ASD
  4. None of the above
8.  Which of the following are reasons for the lack of rigorous scientific studies on treatment efficacy in ASD?
  1. Randomized and controlled ASD treatment efficacy studies are very expensive to conduct
  2. Rigorous treatment efficacy studies on ASD take a long time to conduct
  3. The outcomes involved in ASD treatment efficacy studies are difficult to measure
  4. All of the above are reasons for the lack of rigorous scientific studies on ASD treatment effectiveness.
9.  When published evidence is lacking, what is the ethical way to proceed?
  1. Review expert opinion and select an approach that has the most overlap with current theories
  2. Suspend use of any approaches that lack any evidence
  3. Base your decision on positive or negative experiences you have personally had with the approach
  4. Mix several popular ideas into your treatment so that at least one of them might have a chance of working
10.  A free on-line resource that can assist with locating academic articles dealing with treatment efficacy is:
  1. Wikipedia
  2. WebMD
  3. AutismAbout.com
  4. Google Scholar