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Neurobiology of Addiction: Implications for Occupational Therapy Intervention

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1.  Addiction is a ________________. Choice Choice which becomes a disease over time Chronic relapsing disease Dysfunction of our society

2.  Addiction affects an individual's ____________. Personal relationships Work habits/skills IADL/Self care All of the above

3.  Dopamine spikes impair the addict's ability to: Learn new concepts Consistently abstain from use Control behaviors All of the above

4.  All of the following statements are true EXCEPT: Children of alcoholics are 3 to 4 times more likely to be alcoholic than the general population The environment a child is raised in determines their propensity for addiction Biological children of alcoholics have a much higher risk of alcoholism regardless of who parents them Twins separated at birth had the same results by age 30 as children raised in birth families

5.  The brain function in the addict is: Normal in every aspect until first exposure to an addictive substance Heals quickly when drug use stops Different from the non-addicted brain before the first use Can be changed if the person have a strong will to change

6.  All of the following statements regarding what occurs in the brain following repeated substance use are true EXCEPT: Normal pleasure cannot compete, they lose relative value Repeated exposure causes a blunted response to everyday experiences Normal drives hierarchy is disrupted and replaced with new priorities The brain quickly returns to normal when substance use ends

7.  Which statement is NOT correct regarding Corticotrophin Releasing Factor (CRF)? CRF causes increase in dopamine and glutamate in the addict's limbic region Elevated CRF decreases cravings and relapse CRF interaction with dopamine resets hedonic set point CRF is activated for several months after withdrawal

8.  Which statement is TRUE regarding addiction's effect on learning? Procedural learning is rigid. Procedural learning is life long. Procedural learning is partially unconscious. All of the above

9.  All of the following statements regarding denial are true EXCEPT: Denial can be a healthy response to trauma Denial interferes with seeking treatment and leads to relapse Denial is the only river in Egypt The brain is hardwired for denial - addiction hijacks the denial system

10.  Certain activities will cause a spike in dopamine. Which of these activities should be avoided? Relaxation therapy Yoga Massage None of the above