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What are the sympathetic changes that we typically observe after nerve injury?

Rebecca Neiduski, Ph.D., OTR/L, CHT

November 11, 2014

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Question

What are the sympathetic changes that we typically observe after nerve injury? 

Answer

Sympathetic loss results in vasomotor, sudomotor, pilomotor, and trophic changes.  Vasomotor changes are the first.  We will see in a patient with a nerve injury changes in skin temperature, skin color, changes in swelling, and changes in cold intolerance.  It becomes very difficult for these people to be out in cold temperatures for long periods of time.  I think one of the best quick tricks for cold intolerance is warming packs. If you go to a sporting goods store, they carry these for hunting and other sports.  You pop them open and you can put them in your gloves very safely.  They can really improve the amount of heat that can be produced within a glove. 

Secondly with sudomotor, you see changes in sweat patterns.  You will see no sweating or hypohidrosis in denervated areas.  So if you have lost sensation, you have also lost the ability to sweat.   If you have a partial nerve injury, you can also see hyperhidrosis or excessive sweating. 

Pilomotor changes are going be the absence of that gooseflesh response or “goosebumps.”

With trophic changes, you can see changes in skin texture,  atrophy of the finger pulps, changes in the nail beds, changes in hair growth, and slower skin healing.  All of these are sympathetic effects of nerve injuries that can also be observed.  Any of these observations that I make clinically I document in the chart.  

Editor’s note: This Ask the Expert was adapted from the course, ‘The Hand 101’ that is available in text and video course formats. 


rebecca neiduski

Rebecca Neiduski, Ph.D., OTR/L, CHT

Rebecca Neiduski received her Master’s in Occupational Therapy from Washington University and a PhD in Education from Saint Louis University. She serves as the Dean of the School of Health Sciences at Elon University in North Carolina. Becky has educated therapists in Guatemala, Romania, Egypt, Saudi Arabia, and South Africa, and has contributed to medical missions in Guatemala, Haiti, Nicaragua, and Cambodia. Becky was honored with the ASHT Paul Brand Award of Professional Excellence in 2014 and the ASHT Nathalie Barr Lectureship Award in 2016.


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